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Metarrestin;ML246
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Details:
Theoretical analysis
CAS NO.:1443414-10-5
Molecular Formula:C₃₁H₃₀N₄O
Molecular Weight:474.6
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Metarrestin (ML246) disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.
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