MC180295

CAS NO.:2237942-08-2

Molecular Formula:C₁₇H₁₈N₄O₃S

Molecular Weight:358.41

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

MC180295 ((rel)-MC180295) is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.

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Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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