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ARV-771
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Details:
Theoretical analysis
CAS NO.:1949837-12-0
Molecular Formula:C₄₉H₆₀ClN₉O₇S₂
Molecular Weight:986.64
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively.
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Quality control data
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