OGT-IN-2

CAS NO.:442665-87-4

Molecular Formula:C₂₃H₂₇ClN₂O₃S

Molecular Weight:446.99

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Ogt-in-2 is an o-GLCNAC transferase (OGT) inhibitor with IC50 of 53 M.Ogt-in-2 depletes cells of alanine, reducing glucose consumption by cancer cells.Ogt-in-2 reduced endoplasmic reticulum stress and apoptosis markers IN gestational diabetes mice, and reduced neural tube defects IN diabetic mice embryos.

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