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SP-146;SP-96

Catalog No.: R2123614
CAS No.: 2682114-54-9
Formula: C₂₅H₂₀FN₇O
Weight: 453.47
Details:
Theoretical analysis

CAS NO.:2682114-54-9

Molecular Formula:C₂₅H₂₀FN₇O

Molecular Weight:453.47

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
SP-96 is a highly potent, selective and non-ATP-competitive Aurora B (IC50=0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening, incluing MDA-MD-468 (GI50=107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC).
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Quality control data

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