CMPD101

CAS NO.:865608-11-3

Molecular Formula:C₂₄H₂₁F₃N₆O

Molecular Weight:466.458

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

CMPD101 is a potent, highly selective and membrane-permeable inhibitor of GRK2 and GRK3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50 of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, res

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