SHA68

CAS NO.:847553-89-3

Molecular Formula:C₂₆H₂₄FN₃O₃

Molecular Weight:445.485

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

SHA 68 is a potent and selective antagonist of non-peptide neuropeptide S receptor (NPSR) with IC50 of 22.0 nM and 23.8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 limits the blood-brain barrier (BBB) penetration and the activity in neuralgia

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