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TL12-186

Catalog No.: R2101263
CAS No.: 2250025-88-6
Formula: C44H51ClN10O9S
Weight: 931.46
Details:
Theoretical analysis

CAS NO.:2250025-88-6

Molecular Formula:C44H51ClN10O9S

Molecular Weight:931.46

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
TL12-186 is a CRBN-dependent multi-kinase PROTAC decompressor.Including CDK, BTK, FLT3, Aurora Kinases, TEC, ULK, ITK, etc.TL12-186 inhibited CDK2/cyclin A and CDK9/cyclin T1 with IC50 values of 73 and 55 nM, respectively.
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Quality control data

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