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Phthalazinone pyrazole

Catalog No.: R21042813
CAS No.: 880487-62-7
Formula: C18H15N5O
Weight: 317.345
Details:
Theoretical analysis

CAS NO.:880487-62-7

Molecular Formula:C18H15N5O

Molecular Weight:317.345

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase with IC50 of 31 nM. Phthalazinone pyrazole inhibits the proliferation of HCT116, COLO 205, and MCF-7 cells with IC50 of 7.8 μM, 2.9 μM, and 1.6 μM, respectively.
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Quality control data

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