ARQ-252;SHR0302

CAS NO.:1445987-21-2

Molecular Formula:C₁₈H₂₂N₈O₂S

Molecular Weight:414.48

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

SHR0302 is a potent oral active INHIBITOR of JAK, especially JAK1. SHR0302 was more than 10 times more selective to JAK1 than JAK2, 77 times more selective to JAK3, and 420 times more selective to Tyk2. SHR0302 inhibits jak1-STAT3 phosphorylation and in

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