SNDX-5613

CAS NO.:2169919-21-3

Molecular Formula:C₃₂H₄₇FN₆O₄S

Molecular Weight:630.82

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Sndx-5613 is a potent and specific menin-MLL inhibitor, binding Ki at 0.149 nM and inhibiting MENin-MLL with IC50 of 10-20 nM in cell experiments. Sndx-5613 can be used to study MLL gene rearrangement in acute leukemia, including acute lymphoblastic leuk

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