CPD3616

CAS NO.:2140807-05-0

Molecular Formula:C₂₉H₂₆FN₅O₃S

Molecular Weight:543.61

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Jbj-04-125-02 is a potent, selectively mutated, allosteric, and orally active EGFR inhibitor with an IC50 of 0.26 nM against EGFRL858R/T790M. Jbj-04-125-02 can inhibit the proliferation of cancer cells and signal transduction of EGFRL858R/T790M/C797S. J

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