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CU-CPT-9a
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Details:
Theoretical analysis
CAS NO.:2162962-69-6
Molecular Formula:C16H13NO2
Molecular Weight:251.28
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF-ĸB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
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