BMS-195614

CAS NO.:253310-42-8

Molecular Formula:C₂₉H₂₄N₂O₃

Molecular Weight:448.512

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

BMS 195614 is a neutral RAR α-selective antagonist (Ki = 2.5 nM) and exhibits no significant effect on nuclear receptor corepressor (NCoR) binding. BMS 195614 moderately decreases SMRT binding to RAR and agonist-induced coactivator (CoA) recruitment. Also it is a derivative of retinoic acid.

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