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SGC-SMARCA-BRDVIII

Catalog No.: R2202113
CAS No.: 1997319-84-2
Formula: C19H25N5O3
Weight: 371.43
Details:
Theoretical analysis

CAS NO.:1997319-84-2

Molecular Formula:C19H25N5O3

Molecular Weight:371.43

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2/4 and PB1(5), with Kds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3), with Kds of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts.
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Quality control data

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