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Rineterkib;ERK-IN-1

Catalog No.: R2202157
CAS No.: 1715025-32-3
Formula: C26H27BrF3N5O2
Weight: 578.42
Details:
Theoretical analysis

CAS NO.:1715025-32-3

Molecular Formula:C26H27BrF3N5O2

Molecular Weight:578.42

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Rineterkib (compound B) is an orally active RAF and ERK1/2 inhibitor in the study of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer.
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Quality control data

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