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Lisaftoclax; APG-2575; Bcl-2/Bcl-xl inhibitor 1
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Details:
Theoretical analysis
CAS NO.:2180923-05-9
Molecular Formula:C45H48ClN7O8S
Molecular Weight:882.4227
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively.
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Quality control data
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