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Bumetanide
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Details:
Theoretical analysis
CAS NO.:28395-03-1
Molecular Formula:C17H20N2O5S
Molecular Weight:364.42
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively.
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Quality control data
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