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Sephin 1

Catalog No.: R2304234
CAS No.: 951441-04-6
Formula: C8H9ClN4
Weight: 196.64
Details:
Theoretical analysis

CAS NO.:951441-04-6

Molecular Formula:C8H9ClN4

Molecular Weight:196.64

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect.
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