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7-CKA sodium salt

Catalog No.: R2304299
CAS No.: 1263094-00-3
Formula: C10H5ClNNaO3
Weight: 245.59
Details:
Theoretical analysis

CAS NO.:1263094-00-3

Molecular Formula:C10H5ClNNaO3

Molecular Weight:245.59

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery.
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