N-乙酰基-4-苯醌亚胺

CAS NO.:50700-49-7

Molecular Formula:C₈H₇NO₂

Molecular Weight:149.15

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

NAPQI is the toxic metabolite of Acetaminophen (HY-66005). It is also an inhibitor of enzymes in the vitamin K cycle. It is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver.

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