GNE-7883

CAS NO.:2648450-42-2

Molecular Formula:C₂₈H₂₉FN₆O₂

Molecular Weight:500.57

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

GNE-7883 is a pan-TEAD inhibitor with anti-cell proliferation activity. It overcomes resistance to KRAS G12C inhibitors in multiple preclinical models by inhibiting YAP/TAZ activation. GNE-7883 may be used in the study of YAP/TAZ-dependent cancers.

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