VU0409106

CAS NO.:1276617-62-9

Molecular Formula:C₁₅H₁₁FN₄O₂S

Molecular Weight:330.34

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

VU0409106 is a potent and selective mGlu5 negative allosteric modulator (NAM) with an IC50 of 24 nM. It shows anxiolytic effects in rat models in a concentration-dependent manner. It also penetrates the blood-brain barrier (BBB).

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