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NPS-2143 hydrochloride

Catalog No.: R240402140
CAS No.: 324523-20-8
Formula: C24H25N2O2Cl.HCl
Weight: 445.38144
Details:
Theoretical analysis

CAS NO.:324523-20-8

Molecular Formula:C24H25N2O2Cl.HCl

Molecular Weight:445.38144

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. It blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.
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Quality control data

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