Pifithrin-α

CAS NO.:60477-38-5

Molecular Formula:C₁₅H₁₃N₃O₂S

Molecular Weight:299.3476

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. It is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED50=30 nM). It behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.

We offer significant discount for larger quantity order.

For quotation, question, and order, please send email to sales@rechemscience.com

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

Fast delivery about 4-5 working days.