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ADH-6

Catalog No.: R240402221
CAS No.: 2227429-65-2
Formula: C29H36N8O9
Weight: 640.64
Details:
Theoretical analysis

CAS NO.:2227429-65-2

Molecular Formula:C29H36N8O9

Molecular Weight:640.64

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
ADH-6 is a tripyridylamide compound. It abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases.
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