Abemaciclib metabolite M18 hydrochloride

CAS NO.:2704316-82-3

Molecular Formula:C₂₅H₂₉ClF₂N₈O

Molecular Weight:531.000570058823

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.

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