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Aprocitentan(ACT-132577)
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Details:
Theoretical analysis
CAS NO.:1103522-45-7
Molecular Formula:C16H14Br2N6O4S
Molecular Weight:546.193159580231
Purity: > 98%
Solubility (R.T.: 25℃): DMSO
Stability: - 20℃ 2 years
Description
Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.
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Quality control data
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
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