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Aprocitentan(ACT-132577)

Catalog No.: RH133061
CAS No.: 1103522-45-7
Formula: C16H14Br2N6O4S
Weight: 546.193159580231
Details:
Theoretical analysis

CAS NO.:1103522-45-7

Molecular Formula:C16H14Br2N6O4S

Molecular Weight:546.193159580231

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Description
Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.
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Quality control data

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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