| R2032933 |
IRAK inhibitor 6 |
IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor associated kinase 4 (
|
| R2032934 |
SB649868;GSK649868 |
SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor
|
| R2032935 |
Vadadustat |
Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxyl
|
| R2032936 |
Valbenazine |
Valbenazine is a prodrug of the (+)-α isomer of Ro 1-9569 for tardive syndrome t
|
| R2032937 |
VH298 |
VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value
|
| R2032938 |
AG881 |
Vorasidenib (AG-881) is an orally available, brain penetrant second-generation d
|
| R2032939 |
AX-024 hcl |
AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interacti
|
| R2032940 |
AZD3839 |
AZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6
|
| R2032941 |
CFI-402257 |
CFI-402257 is a highly potent and selective TTK (threonine tyrosine kinase) Inhi
|
| R2032942 |
Cobicistat |
Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) enz
|
| R2032943 |
Exatecan Mesylate |
Exatecan Mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.
|
| R2032944 |
Glecaprevir;ABT-493 |
Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging f
|
| R2032945 |
GNE140 |
(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of
|
| R2032946 |
GSK2330672;Linerixibat |
Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active api
|
| R2032947 |
GSK5182 |
GSK5182 is a highly selective inverse agonist of estrogen-related receptor γ (ER
|
| R2032948 |
GSK561679A;Verucerfont |
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist wit
|
| R2032949 |
KIRA6 |
KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of
|
| R2032950 |
LTURM34 |
LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM).LTURM34 exhibits 170-fold se
|
| R2032951 |
LY2955303 |
LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagoni
|
| R2032952 |
MK-7655(Relebactam) |
Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectr
|
| R2032953 |
PD128907 |
PD 128907 is a selective dopamine D2/D3 receptor agonist, with Kis of 1.7, 0.84
|
| R2032954 |
Rotigotine hydrochloride |
Rotigotine (N-0437; N-0923) is a full agonist of dopamine receptor, a partial ag
|
| R2032955 |
Sitravatinib;MGCD516 |
Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK)
|
| R2032956 |
VO-Ohpic trihydrate |
VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC50 of 46±10 n
|
| R2032957 |
3-TYP |
3-TYP is a selective SIRT3 inhibitor, with an IC50 of 16 nM, more potent over SI
|