R10411 |
Ivacaftor;VX770 |
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFT
|
R10412 |
Vemurafenib (PLX4032, RG7204) |
Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with
|
R10414 |
Lomeguatrib |
Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with I
|
R10415 |
AZD1981 |
AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM
|
R10417 |
EHop016 |
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-
|
R10421 |
Optovin |
Optovin is a reversible photoactivated TRPA1 activator.
|
R10422 |
BRD73954 |
BRD73954 is a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM
|
R10423 |
STF118804 |
STF-118804 is a highly specific NAMPT inhibitor.
|
R10424 |
JNJ26481585; Quisinostat |
Quisinostat is an orally available, potent, hydroxamate, pan-HDACi with broad ac
|
R10425 |
Spautin 1 |
Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells
|
R10427 |
Jaceosidin |
|
R10428 |
eupatilin |
|
R10429 |
Doxorubicin hydrochloride |
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase
|
R10430 |
Rapamycin; Sirolimus |
Rapamycin (Sirolimus) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 c
|
R10431 |
Mitomycin C; Ametycine |
Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces
|
R10432 |
Rivaroxaban; Xarelto; BAY 59-7939 |
Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.
|
R10433 |
Prasugrel |
Prasugrel is a thienopyridine ADP receptor (P2Y12) antagonist, used for the redu
|
R10434 |
PR171; Carfilzomib |
Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5
|
R10435 |
Linagliptin; BI1356 |
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
|
R10436 |
Ambrisentan; BSF208075; LU208075 |
Ambrisentan is a highly selective antagonist of the endothelin-1 type A receptor
|
R10437 |
Darusentan |
Darusentan is a selective endothelin A (ETA) receptor antago
|
R10438 |
Dronedarone Hydrochloride |
Dronedarone HCl is a therapy for the treatment of patients with paroxysmal and p
|
R10439 |
Fasudil; HA-1077 |
HA-1077 inhibits vascular smooth muscle contraction by acting as an intracellula
|
R10440 |
Esmolol |
Esmolol is a cardioselective beta1 receptor blocker with rapid onset,
|
R10442 |
Milrinone |
Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.
|