R10529 |
Perifosine(KRX-0401; NSC 639966; D21266) |
Perifosine (KRX-0401) is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cell
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R10554 |
Ipatasertib;GDC-0068; RG7440 |
Ipatasertib (GDC-0068) is a highly selective pan-Akt inhibitor targeting Akt1/2/
|
R10601 |
CGK733 |
CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
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R10602 |
AR-A014418 |
AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki
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R10607 |
CAL-101;GS-1101 |
CAL-101 (Idelalisib, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM
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R10622 |
Buparlisib Hydrochloride (BKM120 Hydrochloride) |
NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110 with IC50 of 52 n
|
R10626 |
xL019; SAR245409 |
Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ
|
R10768 |
KU-60019 |
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cel
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R10871 |
Dorsomorphin (Synonyms: BML-275; Compound C) |
Dorsomorphin (Compound C) 2HCl is a potent, reversible, selective AMPK inhibitor
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R10872 |
Dorsomorphin dihydrochloride (Synonyms: BML-275 dihydrochloride; Compound C dihydrochloride) |
Dorsomorphin (Compound C) 2HCl is a potent, reversible, selective AMPK inhibitor
|
R10868 |
MK-2206 dihydrochloride |
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM
|
R10859 |
Tacrolimus; FK506 |
Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-proly
|
R10905 |
XL147; SAR245408 |
XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/
|
R10907 |
AMG319 |
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold
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R10920 |
HTH-01-015 |
HTH-01-015 is a potent and selective NUAK1 inhibitor with IC50 of 100 nM, >10
|
R10927 |
Pilaralisib;SAR245408;XL147 |
Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3
|
R10957 |
PI103 |
PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM
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R10958 |
AS605240 |
AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fol
|
R10969 |
HS-173 |
HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM.
|
R10977 |
PIK-294 |
PIK-294 is a highly selective p110δ inhibitor with IC50 of 10 nM, 1000-, 49- and
|
R11026 |
CT98014 |
CHIR-98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-f
|
R11555 |
Ly2584702 |
LY2584702 is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Ph
|
R11565 |
NU7026 |
NU7026 is a potent DNA-PK inhibitor with IC50 of 0.23 μM in
|
R11608 |
Mirin |
Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-a
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R11896 |
deguelin |
Deguelin, a naturally occurring rotenoid, is a potent PI3K/AKT inhibit
|