R11037 |
FPS-ZM1 |
FPS-ZM1 is a high-affinity RAGE inhibitor with a Ki of 25 nM.
|
R11039 |
SW044248;SW-044248 |
SW044248 is a non-canonical topoisomerase I inhibitor, and selectively toxic for
|
R11041 |
LLY 507 |
LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase
|
R10894 |
Elacridar (Synonyms: GF120918; GW0918; GG918; GW120918) |
Elacridar (GF120918; GW0918) is a P-glycoprotein inhibitor, and has been used b
|
R10932 |
BAY 11-7082 |
BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation wit
|
R10966 |
PS-1145 |
PS-1145 is a specific IKK inhibitor with IC50 of 88 nM.
|
R10972 |
SB202190 ; FHPI |
SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50
|
R10999 |
Taladegib;LY2940680 |
Taladegib (LY2940680) binds to the Smoothened (Smo) receptor and potently inhibi
|
R11027 |
G-749 |
G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM
|
R11044 |
ARRY-380 analog |
ARRY-380 analog, an inhibitor of EGFR (ErbB1), is extracted from patent WO201515
|
R11045 |
Danusertib;PHA-739358 |
Danusertib is a pyrrolo-pyrazole and aurora kinase inhibitor with IC50 of 13, 79
|
R11046 |
PHA-680632 |
N/A
|
R11047 |
BMS-3 |
BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2
|
R11048 |
BMS-5 (Synonyms: LIMKi 3) |
BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1
|
R11049 |
PCI34051;PCI-34051 |
PCI-34051 is a potent and selective HDAC8 inhibitor with IC50 of 10 nM, with >
|
R11050 |
SCR7 |
SCR7 is a DNA Ligase IV inhibitor with anticancer activity and is also a CRISPR
|
R11051 |
SB-3CT |
SB-3CT is a potent and competitive matrix metalloproteinase MMP-2 and MMP-9 inhi
|
R11052 |
PF-2545920 |
PF-2545920 is a potent and selective PDE10A inhibitor with IC50&n
|
R11053 |
FIIN-2 |
FIIN-2 is an irreversible inhibitor of FGFR with an IC50 of 3.1, 4.3, 27, and 45
|
R11054 |
AP26113 |
ALK-IN-1 (Brigatinib analog) is a potent and selective active inhibitor of anapl
|
R11055 |
E7080 Mesylate;lenvatinib Mesylate |
Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase in
|
R11056 |
Vandetanib |
N/A
|
R11057 |
Eliglustat hemitartrate (Synonyms: Genz-112638; Eliglustat tartrate) |
Eliglustat tartrate (Genz-112638), a specific inhibitor of glucosylceramide synt
|
R11058 |
Elagolix (NBI-56418) |
Elagolix is a highly potent, selective, orally-active, short-duration, non-pepti
|
R11063 |
Genz-123346 free base |
Genz-123346 (free base) is an inhibitor of GL1 synthase that blocks the conversi
|