| R11253 |
PFK-015 |
PFK-015 is an effective inhibitor of PFKFB3 with IC50 of 110 nM (recombinant PFK
|
| R11254 |
Pirinixic acid (Wy-14643) |
Pirinixic acid (Wy-14643) is a potent agonist of PPARα, with EC50s of 0.63 μM, 3
|
| R11255 |
Dacinostat; NVP-LAQ824 |
Dacinostat is a potent HDAC inhibitor, with an IC50 of 32 nM; Dacinostat also in
|
| R11257 |
Lorediplon |
Lorediplon is a novel non-benzodiazepine, hypnotic drug acting as a GABAA recept
|
| R11259 |
L67;DNA Ligase Inhibitor |
L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I a
|
| R11260 |
NS-398 |
N/A
|
| R11261 |
Ritalin |
N/A
|
| R11262 |
3PO |
N/A
|
| R11263 |
UPF 1069 |
UPF 1069 is a PARP inhibitor, with IC50s of 8 and 0.3 μM for PARP-1 and PARP-2,
|
| R11264 |
SCH58261 |
SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A rec
|
| R11272 |
PHCCC |
PHCCC is a Group I metabotropic glutamate receptor antagonist with EC50 of 6 uM
|
| R11273 |
FCCP (Synonyms: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone) |
FCCP is an uncoupler of oxidative phosphorylation in mitochondria. FCCP induces
|
| R11274 |
NQDI 1 |
NQDI-1 inhibits apoptosis signal-regulating kinase 1 (ASK1) with a Ki of 500 nM
|
| R11275 |
FITM |
N/A
|
| R11278 |
CCF642 |
CCF642 is a novel PDI-inhibiting compound with antimyeloma activity. The IC50 is
|
| R11279 |
IMR-1 |
IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activat
|
| R11280 |
IMR-1A |
N/A
|
| R11282 |
SB431542 |
SB-431542 is a potent and selective inhibitor of ALK5/TGF-β type I Receptor with
|
| R11284 |
PS48 |
PS48 is an activator of PDK1 with an AC50 of 8 μM.
|
| R11288 |
Cytochalasin H |
Cytochalasin is a cell-permeable mycotoxin binding to the barbed end of actin fi
|
| R11289 |
Epetraborole hydrochloride;GSK2251052 hydrochloride |
Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor,
|
| R11290 |
POLYQUATERNIUM-1 |
N/A
|
| R11291 |
AZD 3965 |
AZD3965 is a selective MCT1 inhibitor with a Ki of 1.6 nM, showing 6-fold select
|
| R11294 |
Ceralasertib (Synonyms: AZD6738) |
Ceralasertib (AZD6738) is an orally active and bioavailable inhibitor of AT
|
| R11298 |
Belinostat (PXD101; PX105684) |
Belinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC50 of 27 nM i
|