lox-292;Selpercatinib

CAS NO.:2152628-33-4

Molecular Formula:C₂₉H₃₁N₇O₃

Molecular Weight:525.60

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Selpercatinib (LOXO-292) is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 163, has an IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively. Antineoplastic activity.

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Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

Product will be shipped with supporting analytical data.

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