JNJ-38158471

CAS NO.:951151-97-6

Molecular Formula:C₁₅H₁₇ClN₆O₃

Molecular Weight:364.79

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

JNJ-38158471 is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50=40nM.It also inhibits closely related tyrosine kinases, Ret (180nM) and Kit (500nM).It has no significant activity (>1 microM) against VEGFR-1 and VEGF.

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Quality Control by H-NMR,C-NMR,LC-MS,HPLC.

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