VPC-80051(Racemic)

CAS NO.:877969-69-2

Molecular Formula:C₁₆H₁₃F₂N₃O

Molecular Weight:301.297

Purity: > 98%

Solubility (R.T.: 25℃): DMSO

Stability: - 20℃ 2 years

Vpc-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targeting the RNA binding domain (RBD) of hnRNP A1; It directly interacts with hnRNP A1 RBD and reduces the ar-V7 messenger level and ar-V7 mRNA level in 22Rv1 CRPC cell line.

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