R00314 |
Defactinib |
Defactinib (VS-6063; PF-04554878) is a novel FAK inhibitor with potential antian
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R00315 |
Defactinib hydrochloride;VS-6063 hydrochloride; PF 04554878 hydrochloride |
Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a
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R00318 |
Donepezil;E2020 free base |
Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s o
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R00320 |
olodaterol hydrochloride |
Olodaterol hydrochloride is the hydrochloride salt form of Olodaterol, which is
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R00321 |
RET-IN-1 |
RET-IN-1 is a RET kinase inhibitor extracted from patent WO2018071447A
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R2030458 |
Ulixertinib hydrochloride (BVD-523 hydrochloride; VRT752271 hydrochloride) |
Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, hi
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R2032111 |
ALK2-IN-1;BLU782 |
ALK2-IN-1 is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from pa
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R2032112 |
SRT2104;GSK2245840 |
SRT 2104 is a first-in-class, highly selective and brain-permeable activator of
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R2032113 |
NG25 |
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 n
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R2032114 |
GDC0623;GDC-0623;RG 7421;MEK inhibitor 1 |
GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM,
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R2032115 |
AZD2858 |
AZD2858 is a potent, orally active GSK-3 inhibitor, with IC50s of 0.9 and 5 nM f
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R2032116 |
AZD3463;AZD-3463;ALK/IGF1R inhibitor |
AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquir
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R2032117 |
Ko143 |
Ko 143 is a potent and selective ATP-binding cassette sub-family G member 2 (ABC
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R2032118 |
ABT737;ABT-737 |
ABT-737 is a selective and BH3 mimetic Bcl-2, Bcl-xL and Bcl-w inhibitor with EC
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R2032119 |
A-803467;A803467 |
A 803467 is a selective Nav1.8 sodium channel blocker with an IC50 of 8 nM; over
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R2032120 |
AC55541 |
AC-55541 is a highly selective protease-activated receptor 2 (PAR2) agonist (pEC
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R2032121 |
AGI5198;AGI-5198;IDH-C35 |
AGI-5198 is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.
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R2032122 |
Onalespib;AT13387 |
Onalespib (AT13387) is a potent inhibitor of Hsp90, with a Kd of 0.71 nM.
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R2032123 |
Luminespib;NVP-AUY922;VER-52296 |
Luminespib (NVP-AUY922) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM
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R2032124 |
Cediranib(AZD2171) |
Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase i
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R2032125 |
Temsirolimus;CCI-779 |
Temsirolimus is an inhibitor of mTOR with an IC50 of 1.76 μM.
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R2032126 |
Retigabine |
Retigabine(free base) is a novel anticonvulsant with activity in a broad range o
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R2032127 |
Batimastat;BB94 |
Batimastat is a potent broad spectrum MMP inhibitor with IC50 of 3, 4, 4, 6, and
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R2032128 |
Marimastat;BB2516;TA2516 |
Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of MMP
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R2032129 |
Epoxomicin |
Epoxomicin is a cell-permeable and irreversible proteasome inhibitor, primarily
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