| R10845 |
Veliparib;ABT-888 |
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM a
|
| R10892 |
VX-222; VCH-222; Lomibuvir |
VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase wi
|
| R10893 |
JNJ38431055; APD-597 |
APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with E
|
| R10895 |
Tasimelteon |
N/A
|
| R10896 |
Helioxanthin; ACH126447 |
Helioxanthin(ACH126447) and its analogues exhibit significant in vitro antiviral
|
| R10897 |
SYM2206 |
SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8
|
| R10898 |
Lorlatinib (Synonyms: PF-06463922) |
PF-06463922 is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.0
|
| R10899 |
GSK269962A (Synonyms: GSK 269962) |
GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM f
|
| R10900 |
CL-387785 ; EKI-785 |
CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR with IC50 of
|
| R10901 |
MCC950 sodium (Synonyms: CP-456773 sodium; CRID3 sodium salt) |
MCC950 (CP-456773) sodium is a potent, selective, small-molecule inhibitor of NL
|
| R10902 |
MCC950;CP-456773;CRID3 |
MCC950 (CP-456773) sodium is a potent, selective, small-molecule inhibitor of NL
|
| R10903 |
CEP-33779 |
CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM, >40- and >800-
|
| R10904 |
Irbinitinib; ARRY-380; ONT-380 |
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor with IC5
|
| R10905 |
XL147; SAR245408 |
XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/
|
| R10906 |
GSK163090 |
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagoni
|
| R10907 |
AMG319 |
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold
|
| R10908 |
UNC-2025; UNC2025 |
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of
|
| R10910 |
MK-8776 |
MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-f
|
| R10911 |
Motolimod;VTX-2337; VTX-378 |
Motolimod (VTX-2337) is a selective and potent Toll-like receptor (TLR) 8 agonis
|
| R10912 |
Darolutamide; ODM-201; BAY-1841788 |
ODM-201 is a novel androgen receptor (AR) antagonist that blocks AR nuclear tran
|
| R10913 |
Vipadenant; BIIB014 |
Vipadenant(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less pote
|
| R10914 |
RGB-286638 |
RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/
|
| R10915 |
GSK3235025;EPZ-015666;GSK-3235025 |
EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki
|
| R10916 |
SKF-86002 |
SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits
|
| R10917 |
Radotinib; IY-5511 |
Radotinib(IY-5511) is a novel and selective BCR-ABL1 tyrosine kinase inhibitor w
|