R10882 |
Sunitinib (Synonyms: SU 11248) |
Sunitinib Malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and
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R10859 |
Tacrolimus; FK506 |
Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-proly
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R10891 |
Vatalanib |
Vatalanib (PTK787) 2HCl is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a ce
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R10845 |
Veliparib;ABT-888 |
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM a
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R10892 |
VX-222; VCH-222; Lomibuvir |
VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase wi
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R10893 |
JNJ38431055; APD-597 |
APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with E
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R10895 |
Tasimelteon |
N/A
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R10896 |
Helioxanthin; ACH126447 |
Helioxanthin(ACH126447) and its analogues exhibit significant in vitro antiviral
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R10897 |
SYM2206 |
SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist (IC50= 2.8
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R10898 |
Lorlatinib (Synonyms: PF-06463922) |
PF-06463922 is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.0
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R10899 |
GSK269962A (Synonyms: GSK 269962) |
GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM f
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R10900 |
CL-387785 ; EKI-785 |
CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR with IC50 of
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R10901 |
MCC950 sodium (Synonyms: CP-456773 sodium; CRID3 sodium salt) |
MCC950 (CP-456773) sodium is a potent, selective, small-molecule inhibitor of NL
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R10902 |
MCC950;CP-456773;CRID3 |
MCC950 (CP-456773) sodium is a potent, selective, small-molecule inhibitor of NL
|
R10903 |
CEP-33779 |
CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM, >40- and >800-
|
R10904 |
Irbinitinib; ARRY-380; ONT-380 |
Irbinitinib(ARRY-380; ONT-380) is a potent and selective HER2 inhibitor with IC5
|
R10905 |
XL147; SAR245408 |
XL147 analogue is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/
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R10906 |
GSK163090 |
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagoni
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R10907 |
AMG319 |
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold
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R10908 |
UNC-2025; UNC2025 |
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of
|
R10910 |
MK-8776 |
MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-f
|
R10911 |
Motolimod;VTX-2337; VTX-378 |
Motolimod (VTX-2337) is a selective and potent Toll-like receptor (TLR) 8 agonis
|
R10912 |
Darolutamide; ODM-201; BAY-1841788 |
ODM-201 is a novel androgen receptor (AR) antagonist that blocks AR nuclear tran
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R10913 |
Vipadenant; BIIB014 |
Vipadenant(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less pote
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R10914 |
RGB-286638 |
RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/
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