R10952 |
Cobimetinib;GDC-0973; XL518 |
Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor w
|
R10953 |
ABC294640 |
ABC294640 is an orally bioavailable and selective sphingosine kinase-2 (SphK2) i
|
R10954 |
LY3039478;Crenigacestat |
LY3039478 is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in mos
|
R10955 |
RU-58841 |
N/A
|
R10957 |
PI103 |
PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM
|
R10958 |
AS605240 |
AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fol
|
R10959 |
Cobimetinib R-enantiomer;GDC-0973 R-enantiomer; XL-518 R-enantiomer |
Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib. Cobimet
|
R10961 |
SAR407899 hydrochloride |
SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibito
|
R10962 |
Tenofovir alafenamide hemifumarate (Synonyms: GS-7340 (hemifumarate)) |
GS-7340 (Tenofovir alafenamide) hemifumarate is an investigational oral prodrug
|
R10963 |
GS7340 impurity1 |
Tenofovir alafenamide (GS-7340) is an investigational oral prodrug of Tenofovir.
|
R10967 |
PF-431396 |
PF-431396 is a dual PYK2/FAK inhibitor with IC50 of 11 nM and 2 nM, respectively
|
R10968 |
FPH2; BRD-9424 |
FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-deriv
|
R10969 |
HS-173 |
HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM.
|
R10970 |
BMS-833923 |
BMS-833923 is an orally bioavailable Smoothened antagonist. Phase 2.
|
R10971 |
NU-2058;NU2058 |
NU2058 (O6-(Cyclohexylmethyl)guanine) is a potent, competitive and guanine-based
|
R10973 |
CB-5083 |
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor
|
R10974 |
AZ7371 |
TBA-7371 is a potent, noncovalent DprE1 inhibitor. TBA-7371 has potent antituber
|
R10976 |
STF31 |
STF-31 is a selective glucose transporter GLUT1 inhibitor.
|
R10977 |
PIK-294 |
PIK-294 is a highly selective p110δ inhibitor with IC50 of 10 nM, 1000-, 49- and
|
R10978 |
BIX-01294 |
BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in
|
R10979 |
ML204 |
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 io
|
R10980 |
3-Cyano-7-ethoxycoumarin |
3-Cyano-7-ethoxycoumarin is a fluorogenic cytochrome P-450 substrate that genera
|
R10981 |
UNC0379 |
UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransf
|
R10983 |
MPI-0479605 |
MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1
|
R10984 |
ISX-9 (Synonyms: Isoxazole 9) |
Isoxazole 9 (Isx-9) is a synthetic promotor of adult neurogenesis by triggering
|